Promethazine and codeine ought to be used throughout pregnancy provided that the probable gain justifies the likely threat into the fetus.
Disposal of Unused Promethazine HCl and Codeine Phosphate Oral Answer Recommend sufferers to effectively dispose of unused Promethazine HCl and Codeine Phosphate Oral Option. Suggest sufferers to toss the drug while in the household trash pursuing these measures. one) Remove them from their initial containers and mix them having an undesirable compound, such as applied coffee grounds or kitty litter (this can make the drug fewer attractive to little ones and pets, and unrecognizable to people who could deliberately go with the trash trying to get medication).
Never just take any benzodiazepines or medicines that could cause drowsiness or sleepiness all through cure with Promethazine Hydrochloride and Codeine Phosphate Oral Resolution. Ask your healthcare supplier for a listing of these medicines if You're not certain.
Avoidance and control of nausea and vomiting associated with particular varieties of anesthesia and operation.
Never consider any benzodiazepines or medicines that could potentially cause drowsiness or sleepiness during remedy with Promethazine Hydrochloride and Codeine Phosphate Oral Alternative. Talk to your Health care service provider for a summary of these medicines if you are not certain.
Administration of codeine might be accompanied by histamine launch and will be employed with caution in atopic kids.
If this SPL incorporates inactivated NDCs mentioned from the check here FDA initiated compliance action, They are going to be specified as a result.
Precise studies to check the motion of your drug on parturition, lactation, and advancement on the animal neonate were not completed, but a standard preliminary examine in rats indicated no effect on these parameters.
Some medicines might affect how promethazine will work or promethazine may possibly impact how your other medicines do the job. Know the medicines you're taking. Maintain an index of them with you to point out your healthcare Experienced. In particular inform your Health care Expert if you are taking:
Anaphylactic reactions, as adjunctive therapy to epinephrine along with other common measures, following the acute manifestations are actually controlled.
Codeine is without doubt one of the The natural way transpiring phenanthrene alkaloids of opium derived through the opium poppy; it is classed pharmacologically as being a narcotic analgesic.
The opioid antagonists, naloxone and nalmefene, are distinct antidotes for respiratory depression ensuing from opioid overdose. For clinically substantial respiratory or circulatory melancholy secondary to codeine overdose, administer an opioid antagonist. An antagonist shouldn't be administered from the absence of clinically sizeable respiratory melancholy. Since the duration of opioid reversal is expected to be less than the period of motion of codeine in Promethazine HCl and Codeine Phosphate Oral Option, carefully monitor the affected individual right up until spontaneous respiration is reliably reestablished.
Utilize other supportive measures (like oxygen and vasopressors) from the administration of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require Innovative daily life-assist tactics. Gastric emptying might be helpful in removing unabsorbed drug.
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